The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.

The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).

The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.

We are looking for a motivated Laboratory Technician for the 3D Chromatin Organization group led by Dr. Biola M. Javierre. This contract will part of the project entitled “BALL RELAPSE: Deciphering relapse in B-cell acute lymphoblastic leukemia”, funded by the BALL RELAPSE project (Fundación La Caixa, CaixaResearch Health 2023; ref. H23-00060).

RESEARCH DESCRIPTION

Our research group investigates the generation of B cell lymphocytes and how alterations in this process lead to B cell malignancies, such as B cell acute lymphoblastic leukemia or diffuse large B cell lymphoma. To achieve this, we utilize mouse models and human pri-mary samples, applying cellular and molecular methods, omics, and computational biology. Our ultimate goal is to identify new therapeutic targets and biomarkers for cancer patients to improve their quality of life.

The Javierre Team is a group of passionate scientists with an insatiable thirst for learning about spatio-temporal organization of the DNA. Our group combines cutting-edge exper-imental and bioinformatics approaches to understand the specific 3D chromatin organiza-tion of cell differentiation and malignant transformation. Our long-term goal is to keep taking steps forwards in the fight against cancer. We will be unstoppable until we cure it.

The main research goals of our lab are:

· Defining the cell type-specific 3D chromatin organization along cell differentia-tion.

· Identifying the altered DNA topology in blood cancer.

· Study non-coding mutations to prioritize new candidate genes and pathways relat-ed to cancer.

For more information, please contract 3D Chromatin Organization Research Group's webpage (https://www.javierrelab.com/) and the IJC web page.

MAIN RESPONSABILITIES

· Perform Reporter Assays to validate enhancer activity and CRISPR-based func-tional validation.

· Preparations of omics libraires, including: i) ATAC-seq; ii) CHiP-seq, CUT&RUN or similar; iii) Hi-C or similar.

WHAT WE NEED

General skills

· Strong collaboration and communication skills.

· Organizational skills, proactivity, and ability to manage multiple projects simultaneously.

· Ability to manage varying workloads and work effectively in a team.

· Good level of English, both written and spoken (required); knowledge of Spanish is an asset.

Technical skills

· Professional technical training or Degree in Biology or a related fields.

· Expertise in methodologies related to the main responsibilities.

WHAT WE OFFER

· Temporary contract (Indefinido por actividades científico-técnicas)

· Full time contract of 39 hours per week.

· Highly competitive salary

· Flexible remuneration program (kindergarten and other measures).

· An exciting and innovative research project.

· Be part of a young, collaborative and international work environment with cutting-edge technologies and interdisciplinary teams of scientists, including experts in medicine, immunology, genomics and bioinformatics.

· Incorporation in a multinational and highly collaborative team.

· The stimulating environment of the Barcelona metropolitan area.

DEADLINE
Please submit your application by 21th May 2026.

WHO WE ARE?

What makes us different?

The mission of the Josep Carreras Leukaemia Research Institute is to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of cancer, with a special emphasis on Leukaemia and other malignant blood diseases, with the aim of finding a cure for these diseases.
The IJC’s vision is to be a world-class reference and excellent research center that contributes to the improvement of results, and the cure of patients affected by leukaemia and other malignant haemopathies, through innovation, sustainability, social responsibility, talent, and professional experience.

HR Excellence

In 2019, IJC was honored with the “Human Resources Excellence in Research Award” by the European Commission, recognizing the alignment of our human resources policies with the European Charter for Researchers and Code of Conduct for the Recruitment of Researchers. The Human Resources Strategy for Researchers (HRS4R) guides research centers of excellence in implementing and upholding these standards within their policies, emphasizing training, professional development, and mobility opportunities.
The IJC’s commitment to these values and principles strengthens our internal policies and ensures that our members have the optimal conditions and environment for their professional development.
The Board of Trustees is composed of representatives of the Generalitat de Catalunya (regional government), University of Barcelona, Autonomous University of Barcelona, the City of Badalona and the Jose Carreras International Leukaemia Foundation
The Catalan government provides hard money on an annual basis. The Jose Carreras International Leukaemia Foundation provides start-up funds, project funds as well as financial support for investments.
The JCI has an international scientific advisory board served by prominent researchers from US and Europe.
The IJC has been awarded ERC and other EU grants.

The IJC is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, or other legally protected characteristics.