The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.

The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).

The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.

We are looking for a POSTDOCTORAL RESEARCH to be part of the multidisciplinary research team of the research line focused on the role of distal regulatory elements in gene transcription regulation and malignant transformation led by Biola M. Javierre

RESEARCH DESCRIPTION

We are a group of passionate scientists with an insatiable thirst for learning about spatio-temporal organization of the DNA. Our group combines cutting-edge experimental and bioinformatics approaches to understand the specific 3D chromatin organization of haematopoietic cells and its alteration in blood cancers. Our long-term goal is to keep taking steps forwards in the fight against cancer. We will be unstoppable until we cure it. To do so, we have established a close collaboration with the group lead by Alfonso Valencia, Barcelona Supercomputing Center (https://www.bsc.es/).

The main research goals of our lab are:

• Defining the cell type-specific 3D chromatin organization in human haematopoietic cells.
• Identifying the altered DNA topology in blood cancer
• Study non-coding mutations to prioritize new candidate genes and pathways related to blood cancer based

For more information, please visit 3D Chromatin Organization Research Group's webpage (https://www.javierrelab.com/) and the IJC web page (https://www.carrerasresearch.org/en/3d-chromatin-organization_78766).

MAIN RESPONSABILITIES

• She/he will be part of the multidisciplinary research team focused on the research line.
• Specifically, she/he will lead the computational analysis of the project and coordinate data management.
• She/he will supervise students and support grant applications.

• A high level of motivation and interest.
• PhD degree in bioinformatics, computational biology or similar.
• Expertise, at least, in one of the following areas: genome organization, gene regulation and epigenomics.
• Ability to handle varying workloads and aptitude for teamwork.
• High level of collaborative and communicative skills.
• Good level of English speaking and writing skills (required). Spanish (helpful).

WHAT WE OFFER

• Three years full-funded position. Salary will be adjusted according to the experience of the candidate.
• An exciting and innovative research project
• Working in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute.
• Incorporation in a multinational and highly collaborative team.
• The stimulating environment of the Barcelona metropolitan area.
• We will provide support and training to prepare competitive fellowship applications (e.g., Marie Curie, EMBO, FEBS, HFSP among others)

DEADLINE

Please submit your application by February, 2025.

WHO WE ARE?

What makes us different?

The mission of the Josep Carreras Institute is to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases.
The IJC’s vision is to be a world-class reference and excellent research multicampus that contributes to the improvement of results, and the cure of patients affected by leukemia and other malignant hemopathies, through innovation, sustainability, social responsibility, talent, and professional experience.

HR Excellence

In 2019, IJC was honored with the “Human Resources Excellence in Research Award” by the European Commission, recognizing the alignment of our human resources policies with the European Charter for Researchers and Code of Conduct for the Recruitment of Researchers. The Human Resources Strategy for Researchers (HRS4R) guides research centers of excellence in implementing and upholding these standards within their policies, emphasizing training, professional development, and mobility opportunities.
The IJC’s commitment to these values and principles strengthens our internal policies and ensures that our members have the optimal conditions and environment for their professional development.
The Board of Trustees is composed of representatives of the Generalitat de Catalunya (regional government), University of Barcelona, Autonomous University of Barcelona, the City of Badalona and the Jose Carreras International Leukaemia Foundation
The Catalan government provides hard money on an annual basis. The Jose Carreras International Leukaemia Foundation provides start-up funds, project funds as well as financial support for investments.
The JCI has an international scientific advisory board served by prominent researchers from US and Europe.
The IJC has been awarded ERC and other EU grants.

The IJC is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, or other legally protected characteristics.